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Belzutifan can be a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors might maximize incidence or severity of adverse effects. Check for anemia and hypoxia and decrease belzutifan dose as advisable.elvitegravir/cobicistat/emtricitabine/tenofovir DF increases levels of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Whil